Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of RARRES1 in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates.
Target Information: This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]